Confocal Microscopic Findings in Posterior Polymorphous Corneal Dystrophy.
10.3341/jkos.2013.54.11.1783
- Author:
Beom Seok CHOI
1
;
Young Min PARK
;
Jong Soo LEE
Author Information
1. Department of Ophthalmology, Pusan National University Hospital, Pusan National University & Medical Research Institute School of Medicine, Busan, Korea. jongsool@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Confocal microscopy;
Posterior polymorphous corneal dystrophy
- MeSH:
Corneal Dystrophies, Hereditary;
Descemet Membrane;
Endothelium;
Endothelium, Corneal;
Epithelium, Corneal;
Humans;
Microscopy, Confocal
- From:Journal of the Korean Ophthalmological Society
2013;54(11):1783-1787
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To analyze the features of corneal tissue in patients with posterior polymorphous corneal dystrophy (PPMD) using in vivo confocal microscopy (IVCM). CASE SUMMARY: Three patients with clinically diagnosed PPMD were examined using IVCM. Cross-sectioned corneal images of the corneal epithelium, Bowman's layer, stromal layer, Descemet's membrane, and endothelium were evaluated. IVCM demonstrated a depressed crater-like lesion, hyper-dense streak-like lesion, and surface irregularity of the corneal endothelium. Endothelial hypo-reflective vesicular and band-like lesions were also found. Pleomorphism and polymegathism were present with guttae and hyper-reflective endothelial nuclei. CONCLUSIONS: IVCM is a non-invasive and effective tool to diagnose PPMD.