Thrombocytopenia after Intravitreal Bevacizumab Injection for Macular Edema in Branch Retinal Vein Occlusion.
10.3341/jkos.2013.54.11.1788
- Author:
Soo Han LEE
1
;
Lock Hyun JU
;
Jung Hoon YUM
;
Jin Hyoung KIM
;
Doh Hyung LEE
;
Jong Hyun LEE
Author Information
1. Department of Ophthalmology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Ilsan, Korea. ophtha@naver.com
- Publication Type:Case Report
- Keywords:
Branch retinal vein occlusion;
Intravitreal bevacizumab;
Macular edema;
Thrombocytopenia
- MeSH:
Antibodies, Monoclonal, Humanized;
Diagnosis;
Female;
Humans;
Kidney Failure, Chronic;
Macular Edema*;
Middle Aged;
Platelet Count;
Renal Dialysis;
Retinal Vein Occlusion*;
Retinal Vein*;
Retinaldehyde*;
Thrombocytopenia*;
Tomography, Optical Coherence;
Bevacizumab
- From:Journal of the Korean Ophthalmological Society
2013;54(11):1788-1793
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a rare case of thrombocytopenia after intravitreal bevacizumab injection (IVBI) in a patient with macular edema secondary to branch retinal vein occlusion (BRVO). CASE SUMMARY: A 52-year-old female presented to our clinic with complaints of visual disturbance in her right eye for 2 months. She was receiving hemodialysis therapy 3 times a week for 4 years due to chronic renal failure. Unilateral macular edema secondary to BRVO was observed on fundus examination and was confirmed with optical coherence tomography (OCT). The first IVBI was performed, and an additional injection was given 4 weeks later. Four weeks after the second injection, thrombocytopenia was present. The patient was followed up in our clinic without IVBI for 8 weeks and the platelet count recovered. Thrombocytopenia was reconfirmed after 2 additional monthly injections. After she revisited our clinic without IVBI for 8 weeks, the platelet count recovered without any treatment. CONCLUSIONS: When a patient presents with thrombocytopenia after IVBI with macular edema in BRVO, thrombocytopenia due to IVBI should be considered as a possible diagnosis.
