The Relationship between Uric Acid and Homocysteine Levels based on Alcohol-related Facial Flushing.
10.15384/kjhp.2015.15.3.91
- Author:
Eo Chin KIM
1
;
Jong Sung KIM
;
Won Chul UH
;
Soo Young CHOI
;
Sun Kyung LEE
;
Bog Seon JEONG
Author Information
1. Health Promotion Center, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea.
- Publication Type:Original Article
- Keywords:
Homocysteine;
Uric acid;
Flushing;
Alcohol drinking
- MeSH:
Adult;
Alcohol Drinking;
Flushing*;
Homocysteine*;
Humans;
Korea;
Linear Models;
Male;
Uric Acid*
- From:Korean Journal of Health Promotion
2015;15(3):91-97
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: This study aimed to determine the correlation between blood uric acid and homocysteine levels, based on alcohol-related facial flushing. METHODS: Among male adults who visited a health examination center of a university hospital located in Daejeon, Korea, for a personal health examination from March 2013 to February 2014, 702 subjects were analyzed including 401 subjects without alcohol-related facial flushing and 301 with facial flushing. Pearson's correlation and stepwise multivariate linear regression analyses were performed between the log homocysteine levels and other variables including uric acid. RESULTS: Uric acid showed a significant positive correlation with log homocysteine (gamma=0.166, P=0.001) (beta=0.176; P=0.001) in the non-flushing group. In contrast, none of the variables showed any significant correlations with log homocysteine in the flushing group. CONCLUSIONS: Alcohol users not exhibiting alcohol-related facial flushing showed a positive correlation between uric acid and homocysteine levels, whereas those without facial flushing showed no such correlation.