Predictors and Clinical Features of Long-term Continuous Ambulatory Peritoneal Dialysis(CAPD).
- Author:
Hyun Jung ROH
1
;
Dong Ryul RYU
;
Tae Hyun YOO
;
Hyeong Cheon PARK
;
Suk Kyoon SHIN
;
Sin Wook KANG
;
Kyu Hun CHOI
;
Ho Yung LEE
;
Dae Suk HAN
Author Information
1. Department of Internal Medicine, College of Medicine, Yonsei University, Institute of Kidney Disease, Seoul, Korea. hjroh@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Long-term;
CAPD
- MeSH:
Body Weight;
Creatinine;
Female;
Humans;
Korea;
Nutritional Status;
Nutritional Support;
Peritoneal Dialysis;
Peritoneal Dialysis, Continuous Ambulatory;
Renal Dialysis;
Renal Replacement Therapy;
Retrospective Studies;
Sex Ratio;
Survival Rate;
Survivors
- From:Korean Journal of Nephrology
2001;20(2):306-314
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although CAPD has become firmly established as an effective mode of renal replacement therapy, it's technique survival rate is much inferior compared to hemodialysis. To date, few patients have been maintained on this therapy for more than 10 years. To gain insights into clinical features of patients who had maintained over 10 years on CAPD in Korea, we retrospectively compared 23 patients who survived more than 10 years on PD(Long-term survivors, LTS) and 63 patients who died(Short-term survivors, STS-died, 41 patients) or changed to hemodialysis(STS-HD, 22 patients) within 4 years of initiating PD. For all patients, age, sex, diabetic history, prior cardiac events, body weight and biochemical profiles were analyzed. 1) The LTS were younger(39.7+/-12.4 vs. 47.7+/-12.3 vs. 60.9+/-13.8 years) compared with STS-HD and STS-died. 2) The LTS had less cases of DM(4.3% vs. 31.8 % vs, 61%), and had less cases of prior cardiac events(4.3% vs. 4.5% vs, 34.1%) compared with STS-HD and STS-died. Sex ratio and body weight were comparable in three groups. 3) At the initiation of PD, the LTS had higher serum creatinine(16.7mg/dL vs. 12.4mg/dL vs, 8.4mg/dL), albumin(3.53g/dL vs. 3.27g/dL vs, 3.20g/dL) levels compared with STS-HD and STS-died. 4) During 10 year CAPD treatment, LTS showed relatively stable body weight except the increase of body weight for the first 2 years in female. BUN, creatinine, protein, albumin constantly increased for the first 4 years, and then started to decline by 4 th to 6 th years. In conclusion, young age, non-diabetic history, less prior cardiac events and good nutritional status can predict the long-term survival on peritoneal dialysis. The evaluation of nutritional status and nutritional support by 4 th to 6 th years may be important in maintaining long-term survival in CAPD patients.
