Ischemic Stroke with Extracranial Internal Carotid Artery Occlusion in Essential Thrombocythemia with JAK-2 Mutation.
- Author:
Jee Eun LEE
1
;
A Reum JUNG
;
Ji Hyun CHOI
;
Tae Kyung KIM
;
Eunjin KWON
;
Chan young LEE
;
Min Young CHUN
;
Yoonkyung CHANG
;
Yong Jae KIM
;
Tae Jin SONG
Author Information
- Publication Type:Case Report
- Keywords: Thrombocythemia; Essential; Cerebral infarction; Janus kinase 2
- MeSH: Arteries; Biopsy; Bone Marrow; Brain; Carotid Artery, Internal*; Cerebral Arteries; Cerebral Infarction; Humans; Infarction; Janus Kinase 2; Male; Middle Aged; Platelet Count; Stroke*; Thrombocythemia, Essential*; Thrombocytosis; Thrombosis
- From:Journal of the Korean Neurological Association 2016;34(5):384-387
- CountryRepublic of Korea
- Language:Korean
- Abstract: In essential thrombocythemia (ET), cerebral infarction with large cerebral artery occlusion has rarely been reported. A 53-year-old male was admitted with left sided weakness. Brain magnetic resonance images revealed right internal carotid artery (ICA) territory infarction and proximal ICA occlusion. The blood laboratory examination demonstrated continuously increased platelet count (above 617,000/µL). Increased megakaroycytes and JAK2 V617F mutation were confirmed in the bone marrow biopsy. We should consider the possibility of ET in patient with large artery thrombosis and thrombocythemia.
