Clninical Features of Rotaviral Gastroenteritis in Neonates.
- Author:
Shin I PARK
1
;
Hae Oak KWON
;
Jun Ho LEE
;
Su Jin JUNG
Author Information
1. Department of Pediatrics, College of Medicine, Pochon CHA University, Sungnam, Korea. jinped@hanmail.net
- Publication Type:Original Article
- Keywords:
Rotavirus;
Neonates
- MeSH:
Agglutination;
C-Reactive Protein;
Cyanosis;
Diagnosis;
Diarrhea;
Fever;
Gastroenteritis*;
Humans;
Hygiene;
Infant;
Infant, Newborn*;
Latex;
Leukocytosis;
Occult Blood;
Rare Diseases;
Retrospective Studies;
Rotavirus;
Seizures
- From:Korean Journal of Pediatrics
2005;48(10):1121-1125
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Rotavirus is the main cause of infantile diarrheal disease worldwide, especially in patients 3-24 months of age. Infants younger than 3 months of age are relatively protected by transplacental antibody. So the purpose of this study is to evaluate the clinical features and severity of neonatal rotaviral gastroenteritis less than 1 month of age. METHODS: A retrospective chart review was established of 62 neonates less than 1 month of age and with a diagnosis of rotaviral gastroenteritis who had been admitted to Pochon CHA University between June 2002 through July 2004. The rotavirus was examined by stool latex agglutination. RESULTS: During 2 years, the total number of admitted patients for rotaviral gastroenteritis was 688 and among these, less than 1 month of age accounted for 9% (62). The occurrence was generally even distribution from January to July (7.14+/-1.0) but since then decreased (2.4+/-1.8). The most common chief complaint was mild fever (46%) when admitted which subsided within 1 hospital day in most patients. 4 patients had seizure and cyanosis with no typical symptoms of rotaviral gastroenteritis. During admission, all the patients had diarrhea. 17% of the patients had leukocytosis and positive C-reactive protein. In one patient, stool occult blood test was positive but there was no necrotizing gastroenteritis evidence. The mean period of hospital day was 5.8+/-2.5 and breast-milk feeding was 62.9%. CONCLUSION: Neonatal rotaviral gastroenteritis is not a rare disease. Most patients have fever and diarrhea and improve through conservative therapy but a few patients may have severe complications so we must be more cautious about the hygiene for prevention.