A Case of Anti-Sda Proven by Urine Neutralization Test.
- Author:
Seung Gyu YUN
1
;
Jang Su KIM
;
Jin Hyuk YANG
;
Soo Young YOON
;
Chang Kyu LEE
;
Chae Seung LIM
;
Yunjung CHO
;
Young Kee KIM
;
Kap No LEE
Author Information
- Publication Type:Case Report
- Keywords: Anti-Sda; Urine neutralization test; Mixed field agglutination
- MeSH: Agglutination; Antibody Specificity; Blood Group Incompatibility; Humans; Male; Mass Screening; Neutralization Tests
- From:Laboratory Medicine Online 2011;1(1):64-66
- CountryRepublic of Korea
- Language:Korean
- Abstract: Anti-Sda is of no clinical significance, because it rarely causes hemolytic transfusion reactions. Even when its presence is suspected during antibody screening test, further identification of the antibody is usually not performed. We experienced a case of anti-Sda in 73 yr-old male patient showing mixed field agglutination by microcolumn agglutination. Antibody specificity could not be identified by conventional antibody identification test, and it was proven to be anti-Sda by urine neutralization test. In spite of its little clinical significance, it may give incompatible crossmatching results reacting with Sda antigen, which occurs at a high frequency in general population. When incompatible crossmatch results arising from anti-Sda are suspected, the problem may be solved by using the urine-neutralized serum of in crossmatching test.
