Neurofibromatosis Type 1 with Cerebellar Piloytic Astrocytoma.
- Author:
In Sang JEON
1
;
Jung Sun KIM
;
Ji Hye KIM
;
Na Rae KIM
Author Information
1. Department of Pediatrics, Gachon Medical School, Inchon, Korea. isjeon@ghil.com
- Publication Type:Case Report
- Keywords:
Neurofibromatosis type 1;
Astrocytoma
- MeSH:
Astrocytoma*;
Cafe-au-Lait Spots;
Cerebellum;
Child;
Female;
Glioma;
Humans;
Nervous System Neoplasms;
Neurofibroma;
Neurofibromatoses*;
Neurofibromatosis 1*;
Optic Nerve Glioma
- From:Korean Journal of Pediatrics
2004;47(4):458-461
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neurofibromatosis type 1(NF1) is one of the most common inherited disorders, clinically characterized by cafe-au-lait spots, Lisch nodules and neurofibromas. In addition, the affected individuals usually develop benign and malignant tumors of the nervous system. One of the most common tumors is the optic nerve glioma. NF1-associated glioma, however, rarely occurs in the cerebellum. Recently, we experienced a NF1-associated cerebellar pilocytic astrocytoma in an 11 years old girl. She has a family history of NF1 and multiple cafe-au-lait spots over her whole body. We report herewith a case of NF1-associated cerebellar pilocytic astrocytoma with a brief review of related literature.
