The comparison of monitored anesthesia care with dexmedetomidine and spinal anesthesia during varicose vein surgery.
10.4174/astr.2014.87.5.245
- Author:
Eun Jin MOON
1
;
Ki Woon KANG
;
Jun Young CHUNG
;
Jong Man KANG
;
Je Hoon PARK
;
Jin Hyun JOH
;
Ho Chul PARK
;
Jae Woo YI
Author Information
1. Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea. mdyjwchk@khu.ac.kr
- Publication Type:Clinical Trial ; Original Article ; Randomized Controlled Trial
- Keywords:
Dexmedetomidine;
Monitored anesthesia care;
Sedation;
Spinal anesthesia
- MeSH:
Anesthesia*;
Anesthesia, Spinal*;
Blood Pressure;
Dexmedetomidine*;
Heart Rate;
Humans;
Ketamine;
Midazolam;
Varicose Veins*;
Vital Signs;
Walking
- From:Annals of Surgical Treatment and Research
2014;87(5):245-252
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this study was to investigate the effectiveness and safety of monitored anesthesia care (MAC) using dexmedetomidine for its sedative and analgesic effect during varicose vein surgery. METHODS: Forty-two patients, who underwent varicose vein surgery, were divided into the MAC group (n = 20) or the spinal anesthesia group (n = 22) for randomized clinical trial. In the MAC group, dexmedetomidine was administered by a loading dose of 1 microg/kg for 10 minutes, followed by a maintenance infusion of 0.2-1.0 microg/kg/hr. Ketamine was used for intermittent injection. In the spinal anesthesia group, midazolam was used for sedation. Intraoperative vital signs, the number of adverse events, and the satisfaction of patients and surgeons concerning the anesthetic condition were compared between the two groups. RESULTS: Systolic blood pressure was intraoperatively significantly different over time between the two groups. The groups had statistical differences in the change in heart rate with regard to time. In the postanesthetic care unit, patients and surgeons in the MAC group had a lower satisfaction score, compared to patients and surgeons in the spinal anesthesia group. However, in the recovery period, patients had a positive perception concerning MAC anesthesia. In addition, without significant adverse events, the MAC group had a shorter time to possible ambulation, which indicated an early recovery. CONCLUSION: We believe that MAC using dexmedetomidine in combination with ketamine may be an alternative anesthetic technique for varicose vein surgery with regard to a patient's preference and medical condition.
