Small Cell Carcinoma of the Ovary, Hypercalcemic Type, Large Cell Variant.
- Author:
Jong Sil LEE
1
;
Jong Hak LEE
;
Yu Kyung KIM
;
Sun Hoo PARK
;
Gyung Hyuck KO
Author Information
1. Department of Pathology and Obstetrics and Gynecology, Gyeongsang National University College of Medicine, Jinju 660-751, Korea. gyunghko@gshp.gsnu.ac.kr
- Publication Type:Case Report
- Keywords:
Ovary;
Carcinoma;
Small cell;
Hypercalcemia
- MeSH:
Abdominal Pain;
Adult;
Carcinoma, Small Cell*;
Cytoplasm;
Dysmenorrhea;
Eosinophils;
Epithelial Cells;
Female;
Humans;
Hypercalcemia;
Hysterectomy;
Ovary*
- From:Korean Journal of Pathology
2001;35(5):440-443
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report the clinical and pathological features, including the immunohistochemical and electron microscopic findings, of a case of hypercalcemic type, large cell variant, ovarian small cell carcinoma. A 44-year-old woman complained of abdominal pain and dysmenorrhea. A mass on the left ovary was detected by computer tomographic scan. A total hysterectomy with bilateral salpingo-oophorectomy was done. Histologically, the tumor was predominantly composed of large cells with abundant eosinophilic cytoplasm and prominent nucleoli. Mucin-containing cells and myxoid stroma were also present. Typical follicle-like spaces with lined by small, closely packed epithelial cells with scanty cytoplasm were occasionally seen. No dense core granules were identified on electron microscopic examination.
