Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010.
10.6065/apem.2013.18.3.141
- Author:
Yeon Jin JEON
1
;
In Ah JUNG
;
Shin Hee KIM
;
Won Kyoung CHO
;
Seung Hee JEONG
;
Kyoung Soon CHO
;
So Hyun PARK
;
Min Ho JUNG
;
Byung Kyu SUH
Author Information
1. Department of Pediatrics, The Catholic University of Korea College of Medicine, Seoul, Korea. wendy626@catholic.ac.kr, suhbk@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Ferritins;
Adolescent;
Obesity;
Male;
Korean
- MeSH:
Adolescent*;
Blood Glucose;
Blood Pressure;
Body Mass Index;
Cholesterol;
Cross-Sectional Studies;
Female;
Ferritins*;
Humans;
Insulin;
Leukocytes;
Lipoproteins;
Male*;
Nutrition Surveys*;
Obesity*;
Prevalence;
Triglycerides
- From:Annals of Pediatric Endocrinology & Metabolism
2013;18(3):141-147
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Previous reports show an association between high serum ferritin levels and metabolic syndrome (MS) in adults. In adolescents, little information is available with obesity and serum ferritin levels. METHODS: This is a cross-sectional study. Data were obtained from the 5th Korean National Health and Nutrition Examination Survey (K-NHANES) conducted during 2010 by the Korean Ministry of Health and Welfare. A total of 849 subjects aged 10-18 years participated in the 2010 survey. A body mass index (BMI) > or =95th percentile for age and sex or a BMI > or =25 was used to diagnose as obesity. RESULTS: The weighted prevalence of obesity was 13.4% (62/462) in male and 8.5% (33/387) in female. We observed significantly higher serum ferritin in male than in female (mean+/-standard error [SE], 50.5+/-2.3 microU/L vs. 30.6+/-1.3 microU/L; P<0.0001). In male, serum ferritin is positively correlated with age (P<0.0001). White blood cell (WBC) count, serum fasting blood sugar, triglyceride (TG), total cholesterol, low-density lipoprotein, insulin, homeostasis model assessment-insulin resistance (HOMA-IR), systolic and diastolic blood pressure, and ferritin levels were higher and high-density lipoprotein (HDL) were lower in the obesity than in the normal group. In female adolescents, WBC count, TG, insulin, and HOMA-IR were higher and HDL were lower in the obesity than in the normal group. In male, serum ferritin levels showed positive association with obesity (beta=21.196, P=0.016). CONCLUSION: Serum ferritin levels appear to be associated with obesity in Korean male adolescents.
