Complete Remission of Renal Cell Carcinoma with Metastases to Lung and Bone Following Initial Interferon-alpha Immunotherapy and Adjuvant Nephrectomy.
- Author:
Kwang Yeom LEE
1
;
Jae Hun SHIN
;
Won Jun CHOI
;
Yun Beom KIM
;
Jeong Ki LEE
;
Tae Young JUNG
;
Hong Bang SHIM
Author Information
1. Department of Urology, Seoul Veterans Hospital, Seoul, Korea. hb0282@hanmail.net
- Publication Type:Case Report
- Keywords:
Renal cell carcinoma;
Metastases;
Interferon-alpha;
Nephrectomy
- MeSH:
Aged;
Brain;
Carcinoma, Renal Cell*;
Humans;
Immunotherapy*;
Interferon-alpha*;
Liver;
Lung*;
Neoplasm Metastasis*;
Nephrectomy*;
Prognosis;
Recurrence
- From:Korean Journal of Urology
2004;45(10):1062-1065
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Patients with metastatic renal cell carcinomas have a median survival of less than 1 year and a 0-20% 5-year survial. The immunotherapy agent interferon-alpha has consistently produced objective responses rarely exceeding 20% of treated patients. Moreover, in patients with metastases to brain, liver or bone, the prognosis is extremely poor. A 66-year-old man, with a right renal cell carcinoma, with metastases to lung and bone who had entered a remarkable complete radiological remission of the metastases to lung and bone by 82 months following interferon-alpha immunotherapy, underwent a nephrectomy. The patient has remained recurrence free for 16 months after the nephrectomy.
