Experience with 5-Aminolevulinic Acid in Fluorescence-Guided Resection of a Deep Sylvian Meningioma.
10.3340/jkns.2012.52.6.558
- Author:
Michael P CHAE
1
;
Sang Woo SONG
;
Sung Hye PARK
;
Chul Kee PARK
Author Information
1. University of Melbourne, Melbourne, Victoria, Australia.
- Publication Type:Case Report
- Keywords:
5-aminolevulinic acid;
Resection;
Deep sylvian meningioma;
Meningioma without dural attachment
- MeSH:
Fluorescence;
Meningioma;
Middle Cerebral Artery;
Recurrence
- From:Journal of Korean Neurosurgical Society
2012;52(6):558-560
- CountryRepublic of Korea
- Language:English
-
Abstract:
The 5-aminolevulinic acid (5-ALA)-induced tumor fluorescence is a useful intraoperative marker for the diagnosis and the detection of various malignancies, but its use in meningioma is only reported infrequently. In meningioma, a complete resection of the tumor mass is crucial for the prevention of recurrence and postoperative morbidities. Deep sylvian meningioma is a rare type of meningioma where complete tumor removal is complicated by its deep anatomical location and close involvement with the middle cerebral artery. From our experience, 5-ALA-mediated fluorescence facilitated a safe excision whilst preserving critical neurovascular structures. To our best knowledge, this is first report from use of 5-ALA in a deep sylvian meningioma.
