Two Cases of Prurigo Pigmentosa.
- Author:
Hyun Cheol LEE
;
Suk Keyong LEE
;
Heung Ryul LEE
;
Won Woo LEE
;
Duck Ha KIM
- Publication Type:Case Report
- Keywords:
Prurigo Pigmentosa;
Dapsone
- MeSH:
Dapsone;
Dermis;
Exocytosis;
Female;
Humans;
Hyperpigmentation;
Japan;
Prurigo*;
Pruritus;
Skin Diseases;
Young Adult
- From:Korean Journal of Dermatology
1995;33(5):945-949
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Prurigo pigmentosa is a chror ic pruritic inflammatory dermatosis characterized by erythematous papules in a reticulated pattern that resolve leaving a reticulated, mottled hyperpigmentation and rapidly response to dapsone therapy. Most cases that have been reported are from Japan. We report two cases of prurigo pigmentosa in a 21 year-old female and a 23-year-old female. Histopathologic findings of erythematous papules showed exocytosis, spongiosis, liquefaction degeneration of basal cell layer and perivascular lymphohistiocytic infiltration on the upper dermis. We treated them with dapsone, 100mg daily, which resulted in a remarkable regression of the ery thematous papules and improvenien of pruritus.
