A Case of Diffuse Extensive Metastatic Carcinoma Showing Unusual Clinical Features.
- Author:
Moon Seok SIHN
;
Ho June KWON
;
Young Wook RYOO
;
Jae Bong JUNG
;
Byung Chun KIM
;
Kyu Suk LEE
- Publication Type:Case Report
- Keywords:
Extensive Metastic Carcinoma;
Unusual
- MeSH:
Aged;
Arm;
Biopsy;
Dermis;
Humans;
Islands;
Lung;
Male;
Neoplasm Metastasis;
Paraffin;
Skin;
Thorax
- From:Korean Journal of Dermatology
1995;33(5):956-960
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cutaneous metastases from Internal carcinomas are relatively rare. We report a case of cutaneous metastasis believed t.o originate from primary lung carcinoma in a 69-year-old male patient. The patient presented with localized well defined multiple variable sized, hard eryt,hematous papules, nodules and pustules on the right chest, back and upper arm. Biopsy specimens from the nodules upper chest revealed scatt,ered islands of tumor cells and fi brosis of the dermis. To evaluate the role of p53 protein in the development of skin tumors, we examed p53 expres sion at protein level by imnunoperoxidase stain using monoclonal antimouse human p53 antibody on paraffin embeded tissues The patient died after four months from the appearance of cutaneous lesions.
