A Case of Epidermolytic Keratosis Palmaris et Plantaris.
- Author:
Dae Sung LEE
;
Guk Joo CHOI
;
Young Hwan KIM
;
Eun Joo SEO
;
Won HOUH
- Publication Type:Case Report
- Keywords:
Epidermolytic hyperkeratosis;
Tonofilament;
Keratohyalin
- MeSH:
Cytoplasm;
Female;
Humans;
Hyperkeratosis, Epidermolytic;
Infant;
Intermediate Filaments;
Keratoderma, Palmoplantar*;
Keratosis*;
Microscopy;
Organelles;
Rare Diseases
- From:Korean Journal of Dermatology
1985;23(5):678-681
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epidermolytic keratosis palmaris is a rare disease which shows clinical findings of Unna Thost keratoderma and histopathologic of epidermolytic hyperkeratosis. We report herein a case of epidermolytic keratosis palmaris et plantaris in a 16-month-old female baby. Light microscopy shows marked hyperkeratosis, large irregular keratohyalin granules, and large clear spaces in the granular and upper spinous layers. Eletron microscopic findings shows that the clear spaces are areas of cytoplasm filled with a fibrillar material and cellular organelles. Abnormal clumping of tonofilament and keratohyalin is also present.
