Perianal Extramammary Paget's Disease Associated with an Anal Duct Adenocarcinoma: A Case Report.
- Author:
Kang Youn LEE
1
;
Min Young YUN
;
Sun Keun CHOI
;
Yun Suk HUR
;
Kun Young LEE
;
Sei Joong KIM
;
Young Up CHO
;
Seung Ick AHN
;
Kee Chun HONG
;
Suk Hwan SHIN
;
Kyung Rae KIM
;
Ze Hong WOO
Author Information
1. Department of Surgery, Inha University College of Medicine, Incheon, Korea. woopark@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Paget's disease;
Extramammary;
Anal neoplasm;
Adenocarcinoma
- MeSH:
Adenocarcinoma*;
Anal Canal;
Anus Neoplasms;
Carcinoembryonic Antigen;
Colostomy;
Drug Therapy;
Female;
Fluorouracil;
Genitalia, Female;
Humans;
Middle Aged;
Paget Disease, Extramammary*;
Skin;
Transplants
- From:Journal of the Korean Society of Coloproctology
2005;21(3):174-177
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extramammary Paget's disease occurs commonly on the external female genitalia and rarely occurs in the perianal region. Recently, we experienced a case of perianal extramammary Paget's disease associated with an anal duct adenocarcinoma. The patient was a 60-year-old man. The perianal skin lesion was eczematous and encircled the anus. A wide-excision, split-thickness skin graft and temporal T-loop colostomy were performed. Histopathologically, the tumor was a well-differentiated anal duct adenocarcinoma. There was a prominent pagetoid spread of about 6x4 cm. The tumor cell was positive for carcinoembryonic antigen, but the paget cell was negative. The patient was treated with radiation therapy and with single 5-FU chemotherapy six times. Five months later, the perianal region was nearly normal.
