Two Cases of Weber-Christian Disease.
- Author:
Jong Sun SHIN
;
Ryu Sung KIM
;
Tae Ha WOO
- Publication Type:Original Article
- MeSH:
Biopsy;
Chloroquine;
Fever;
Histiocytes;
Inflammation;
Lymphocytes;
Panniculitis;
Panniculitis, Nodular Nonsuppurative*;
Subcutaneous Fat;
Tibia
- From:Korean Journal of Dermatology
1969;7(1):33-36
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Weber-Christian disease is a relapsing, febrile, nodular, nonsuppurative inflammation of the subcutaneous fat tissue. Many authors reported these cases which illustrate the great variability of the clinical manifestation, such as acute or chronic, fulminating or transient, febrile or non febrile, systemic or cutaneous. Two of our cases have had recurrent painful subeutaneous nodules without fever for several years. Biopsy showed a nonspecific inflammatory panniculitis with lymphocytes chiefly, and small amount of histiocytes and foamy cells. It should be suggested Weber-Christian disease when subcutaneous nodules appear recurrently same areas of the whole body surface except anterior aspects of tibia even if no fever as systemic manifestation. Treatment with steroid and chloroquine diphosphete produced good improvement.
