Extensive Fasciitis in Sclerotic-type Chronic Cutaneous Graft-versus-Host Disease.
- Author:
Seong Hun MOON
1
;
Hyun Woo KIM
;
Hyun Chul PARK
;
Jeong Eun KIM
;
Joo Yeon KO
;
Young Suck RO
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea. drko0303@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Chronic GVHD;
Fasciitis;
Sclerodermoid
- MeSH:
Bone Marrow Transplantation;
Fascia;
Fasciitis;
Female;
Fibrosis;
Graft vs Host Disease;
Humans;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive;
Lower Extremity;
Prognosis;
Skin
- From:Korean Journal of Dermatology
2013;51(7):544-547
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fasciitis can occur very rarely with sclerotic-type chronic cutaneous graft-versus-host disease (GVHD). A 54-year-old woman presented with painful skin tightness on upper and lower limb with limited range of movement. She was diagnosed with chronic myelocytic leukemia 5 years ago and underwent allogeneic bone marrow transplantation. Histopathologically, the interlobular septum of subcutis and fascia were remarkably thickened with fibrosis and moderate inflammatory infiltrates accompanying the dilated lymphatic channels with considerable leakage of lymph fluids. Herein, we report a case of extensive fasciitis as a manifestation of chronic GVHD associated with poor prognosis.
