A Case of Clear Cell Basal Cell Carcinoma.
- Author:
Sun Yong KWON
1
;
Sang Hyun PARK
;
Ui Kyung KIM
;
Kun PARK
;
Seok Don PARK
Author Information
1. Department of Dermatology, Wonkwang University School of Medicine, Iksan, Korea. sdpark@wku.ac.kr
- Publication Type:Case Report
- Keywords:
Basal cell carcinoma;
Clear cell
- MeSH:
Alcian Blue;
Carcinoma, Basal Cell;
Cheek;
Cytoplasm;
Eosinophils;
Hemorrhage;
Humans;
Male;
Mohs Surgery;
Mucins;
Periodic Acid;
Recurrence;
Vacuoles
- From:Korean Journal of Dermatology
2013;51(7):548-551
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clear cell basal cell carcinoma is a rare histological variant of basal cell carcinoma, which is characterized by a variable component of clear cells. We report a case of clear cell basal cell carcinoma in a 53-year-old Caucasian male presented with a red 0.7x0.6 cm sized nodule with central bleeding on left cheek for 2 years. Histological examinations showed multiple dermal tumor lobules nested with basaloid cells of a peripheral palisading pattern. In addition, prominent clear cell changes were observed in the center of large nests. The clear cells showed a single large vacuole in their eosinophilic and granular cytoplasm with eccentric condensed nucleus. The clear tumor cells was stained with periodic acid Schiff and showed incomplete diastase-resistance. Intercellular mucin staining with alcian blue was positive. The tumor was successfully treated with Mohs micrographic surgery and no recurrence has been observed for 6 months.
