Linear Lichen Planus in Hypereosinophilic Syndrome.
- Author:
Seung Bae PARK
1
;
Hae Eul LEE
;
Myung IM
;
Young LEE
;
Young Joon SEO
;
Jeung Hoon LEE
Author Information
1. Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea. jhoon@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome;
Linear lichen planus
- MeSH:
Arm;
Biopsy;
Dermis;
Eczema;
Eosinophils;
Epidermis;
Female;
Humans;
Hypereosinophilic Syndrome;
Keratinocytes;
Lichen Planus;
Lichens;
Lymphocytes;
Skin
- From:Korean Journal of Dermatology
2013;51(7):552-555
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypereosinophilic syndrome (HES) is characterized by chronically increased peripheral blood eosinophil levels and organ damages related to eosinophilic infiltration. Cutaneous manifestations are common (>50%) and non-specific. It is generally manifested as erythematous pruritic eczema. Linear lichen planus has not been reported in HES. A 35-year-old woman was presented with linear brownish papules and plaques on her left arm. She had been diagnosed with HES three years earlier. Initially, the skin lesions were manifested as linear pruritic erythematous plaques, but they gradually transformed into shiny brownish plaques. Skin biopsy specimens showed irregular acanthosis of the epidermis and band-like infiltrations of lymphocytes and eosinophils with necrotic keratinocytes in the papillary dermis. We proposed that the eosinophil infiltration was caused by HES, and that the patient's histological and clinical manifestations should account for linear lichen planus.
