Perspectives of International Human Epigenome Consortium.
- Author:
Jae Bum BAE
1
Author Information
- Publication Type:Review
- Keywords: chromatin; DNA methylayion; histones; methylome; microRNAs
- MeSH: Chromatin; Genome; Genome, Human; Histones; Humans; Korea; MicroRNAs; Republic of Korea; Sulfites; Washington
- From:Genomics & Informatics 2013;11(1):7-14
- CountryRepublic of Korea
- Language:English
- Abstract: As the International Human Epigenome Consortium (IHEC) launched officially at the 2010 Washington meeting, a giant step toward the conquest of unexplored regions of the human genome has begun. IHEC aims at the production of 1,000 reference epigenomes to the international scientific community for next 7-10 years. Seven member institutions, including South Korea, Korea National Institute of Health (KNIH), will produce 25-200 reference epigenomes individually, and the produced data will be publically available by using a data center. Epigenome data will cover from whole genome bisulfite sequencing, histone modification, and chromatin access information to miRNA-seq. The final goal of IHEC is the production of reference maps of human epigenomes for key cellular status relevant to health and disease.
