A Case of Functioning Paraganglioma in Posterior Mediastinum.
- Author:
Chang Hoon CHOI
1
;
Sin Won LEE
;
Gui Hwa JUNG
;
Si Hyung PARK
;
Soon Hee LEE
;
Jung Guk KIM
;
Sung Woo HA
;
Bo Wan KIM
;
Sang Chul LEE
;
Eung Bae LEE
;
Tae In PARK
Author Information
1. Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
Paraganglioma;
Posterior mediastinum;
Hypertension
- MeSH:
Adult;
Chromaffin Cells;
Dyspnea;
Female;
Humans;
Hypertension;
Mediastinum*;
Paraganglioma*;
Pheochromocytoma;
Radionuclide Imaging;
Sympathetic Nervous System;
Thorax
- From:Journal of Korean Society of Endocrinology
2002;17(2):292-296
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paraganglioma is an extraadrenal pheochromocytoma originating from chromaffin cells distributed in the sympathetic nervous systems. Functioning extraadrenal paragangliomas represent more than 10% of all pheochromocytomas, and seems to be highly malignant tumor in comparison to intraadrenal pheochromocytomas. Recently, we experienced a case of a paraganglioma in the posterior mediastinum. A 32-year-old woman was admitted to hospital due to dyspnea on exertion, and intractable hypertension. A chest X-ray showed a well-defined mass density on the right cardiac border, and biochemical studies showed characteristic findings of pheochromocytoma. A solitary pheochromocytoma was located in the posterior mediastinum using 131I-MIBG scintigraphy. The clinical manifestations, including hypertension and dyspnea were improved after operation.