Circadian Rhythms in Urinary Functions: Possible Roles of Circadian Clocks?.
- Author:
Jong Yun NOH
1
;
Dong Hee HAN
;
Ji Ae YOON
;
Mi Hee KIM
;
Sung Eun KIM
;
Il Gyu KO
;
Khae Hawn KIM
;
Chang Ju KIM
;
Sehyung CHO
Author Information
1. Graduate Program for Neuroscience, Kyung Hee University School of Medicine, Seoul, Korea. sehyung@khu.ac.kr
- Publication Type:Review
- Keywords:
Circadian clocks;
Urinary bladder;
Urination;
Urinary function
- MeSH:
Biological Clocks;
Circadian Clocks;
Circadian Rhythm;
Humans;
Mammals;
Physiological Processes;
Rodentia;
Urinary Bladder;
Urination
- From:International Neurourology Journal
2011;15(2):64-73
- CountryRepublic of Korea
- Language:English
-
Abstract:
Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and nocturnal rodents, the precise mechanisms of these variations are as yet unclear. In this review, we briefly introduce circadian clocks and their organization in mammals. We then summarize known daily or circadian variations in urinary function. Importantly, recent findings by others as well as results obtained by us suggest an active role of circadian clock genes in various urinary functions. Finally, we discuss possible research avenues for the circadian control of urinary function.
