Nodular Hidradenocarcinoma.
- Author:
Bo Young CHUNG
1
;
Soo Ick CHO
;
In Su AHN
;
Hee Bong LEE
;
Hye One KIM
;
Kwang Ho KIM
;
Chun Wook PARK
;
Cheol Heon LEE
Author Information
1. Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea. dermlee@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Nodular hidradenocarcinoma
- MeSH:
Aged;
Antibodies;
Carcinoma, Papillary;
Cytoplasm;
Eosinophils;
Humans;
Keratins;
Mitosis;
Mucin-1;
Necrosis;
Neoplasm Metastasis;
Recurrence;
Skin
- From:Korean Journal of Dermatology
2011;49(3):250-254
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nodular hidradenocarcinoma was first reported as a clear-cell papillary carcinoma by Liu et al. in 1949. With a potential for uncontrollable local recurrence, it tends to metastasize and often causes death. We report a case of a 68-year-old man with nodular hidradenocarcinoma on the left preauricular area. Histopathology of the tumor showed a multilobulated intradermal mass. In the tumor nodule, there were many cystic spaces of various sizes, resulting from tumor necrosis. The tumor consisted of large, atypical, polygonal cells with eosinophilic cytoplasm, and clear cells with clear cytoplasm. Numerous mitoses were evident. We obtained positive results from an immunohistochemical study with antibodies to cytokeratins, epithelial membrane antigen, and PAS. The patient was treated with a wide local excision. However, we observed a recurrence one month later and performed a wide excision and local skin flap. There has been no evidence of recurrence or metastasis for six months after the second excision.
