Infestation state of clonorchis sinensis in patients with pancreatobiliary diseases in ulsan: based on bile examination.
- Author:
Ki Young LEE
1
;
Kwang Ro JOO
;
Hyun Soo KIM
;
Su Jin SIN
;
Hyo Sup LEE
;
Tae Guen YUN
;
Yeon Ik CHOO
;
Jong Ho PARK
;
Jung Woo SHIN
;
Sung Jo BANG
;
Do Ha KIM
;
Neung Hwa PARK
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.
- Publication Type:Original Article
- Keywords:
Clonorchis sinensis;
Bile;
Pancreatic disease;
Biliary tract disease
- MeSH:
Ampulla of Vater;
Bile Duct Neoplasms;
Bile*;
Biliary Tract Diseases;
Cholangiography;
Cholangitis;
Clonorchiasis;
Clonorchis sinensis*;
Drainage;
Eggs;
Endemic Diseases;
Gallbladder Neoplasms;
Gallstones;
Humans;
Korea;
Male;
Ovum;
Pancreatic Diseases;
Pancreatic Neoplasms;
Ulsan*
- From:Korean Journal of Medicine
2004;66(5):521-525
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Bile examination is believed to be the most precise method for detecting Clonorchis sinensis (CS) eggs. We carried out bile examination to evaluate infestation state of CS in patients with pancreatobiliary diseases in Ulsan, known as an endemic area of CS infestation. METHODS: We examined CS eggs in bile in three hundreds and nine patients with pancreatobiliary diseases. The bile was obtained from endoscopic nasobiliary or percutaneous transhepatic biliary drainage tubes. RESULTS: The overall egg positive rate was 27.5% (35.3% in male, 17.6% in female). The egg positive rate was not significantly different according to the age group: 20.0% in thirties, 26.7% in forties, 24.2% in fifties, 29.9% in sixties, 36.2% in seventies and 16.7% in eighties or more. The egg positive rate according to the disease, except CS cholangitis, was not also statistically different: 32.6% in bile duct cancer, 38.5% in gallbladder cancer, 11.1% in ampulla of Vater cancer, 24.0% in pancreatic cancer, 26.4% in gallstone diseases and 12.5% in the reminder. The location of gallstone and whether CS related diseases or CS unrelated diseases did not affect the egg positive rates. The egg positive rate in patients with normal radiological findings including cholangiography was 17.0%. CONCLUSION: This result shows that regardless of age, sex, and sorts of diseases, the infestation rate of CS was very high. On the basis of our results, it is therefore presumes that clonorchiasis is still endemic disease in Korea.
