A Case of Propofol-Induced Oropharyngeal Angioedema and Bronchospasm.
- Author:
Byung Chul YOU
1
;
An Soo JANG
;
Ji Su HAN
;
Hong Woo CHEON
;
Jong Suk PARK
;
June Hyuk LEE
;
Sung Woo PARK
;
Do Jin KIM
;
Choon Sik PARK
Author Information
- Publication Type:Case Report
- Keywords: Bronchial spasm; angioedema; anaphylaxis; propofol
- MeSH: Aged; Anaphylaxis; Anesthesia; Angioedema; Bronchial Spasm; Edema; Emulsions; Female; Humans; Hypersensitivity; Outpatients; Phospholipids; Propofol; Skin Tests; Soybean Oil; Soybeans
- From:Allergy, Asthma & Immunology Research 2012;4(1):46-48
- CountryRepublic of Korea
- Language:English
- Abstract: Propofol (2,6-diisopropylphenol) is an ultrashort-acting sedative agent with sedative and amnestic effects that is used not only for anesthesia but also for sedation during minor outpatient procedures and endoscopic examinations. Rare cases of anaphylaxis following propofol administration have been reported in the medical literature. Documentation of anaphylaxis is often lacking because the cause and effect relationship is often hard to prove. Only a minority of patients get referred for allergy testing to confirm the offending drug. Here we report a 74-year-old woman who had an anaphylactic reaction with severe oropharyngeal edema and bronchospasm for a few minutes after receiving propofol during endoscopic examination. An allergy skin test was positive for both propofol and soybean. Soybean in the intralipid is one component of propofol, and we concluded that this anaphylaxis was caused by soybean.
