The Association between Oxidative Stress and Metabolic Syndrome in Adults.
10.4082/kjfm.2013.34.6.420
- Author:
So Won CHUNG
1
;
Sung Goo KANG
;
Jun Seung RHO
;
Ha Na KIM
;
In Sun SONG
;
Yun Ah LEE
;
Soo Jeong HEO
;
Sang Wook SONG
Author Information
1. Department of Family Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. sswkoj@unitel.co.kr
- Publication Type:Original Article
- Keywords:
Metabolic Syndrome;
Reactive Oxygen Species;
Oxidative Stress;
High-Sensitivity C-reactive Protein
- MeSH:
Adult*;
Alanine Transaminase;
Biomarkers;
Blood Glucose;
C-Reactive Protein;
Cholesterol;
Cholesterol, HDL;
Fasting;
Female;
Health Promotion;
Humans;
Life Style;
Linear Models;
Lipoproteins;
Male;
Oxidative Stress*;
Oxygen;
Reactive Oxygen Species
- From:Korean Journal of Family Medicine
2013;34(6):420-428
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: In this Study, we investigated the effects of lifestyle and metabolic syndrome on free oxygen radical levels in men and women in Korea. METHODS: A total of 254 adults were included in this study from February 2011 to June 2012 at a health promotion center. Information of the lifestyles and presence of metabolic syndrome factors was obtained. Biochemical markers were measured and free oxygen radicals test (FORT) was performed on the blood. RESULTS: Of the 254 subjects, 86 (33.9%) had metabolic syndrome, and 187 (73.6%) were men. Between the subjects with and without metabolic syndrome, there was a significant increase in alanine aminotransferase and serum FORT values in the subjects with metabolic syndrome. Multiple linear regression analysis showed that high-sensitivity C-reactive protein (hs-CRP) (P = 0.004), metabolic syndrome (P = 0.037), and female gender (P = 0.030) were independent predictors of serum FORT values. The subjects with high fasting blood sugar level or low high density lipoprotein cholesterol levels showed high serum FORT values. CONCLUSION: High hs-CRP, the presence of metabolic syndrome, and female gender were associated with the high oxidative stress. High oxidative stress was associated with the presence of metabolic syndrome.
