Idiopathic Granulomatous Vulvitis.
- Author:
Seo Wan KIM
1
;
Tae Seok KONG
;
Tae Young HAN
;
June Hyunkyung LEE
;
Sook Ja SON
Author Information
1. Department of Dermatology, Eulji Medical Center, College of Medicine, Eulji University, Seoul, Korea. ssjmdderma@hanmail.net
- Publication Type:Case Report
- Keywords:
Idiopathic granulomatous vulvitis
- MeSH:
Adult;
Biopsy;
Crohn Disease;
Dermis;
Edema;
Epithelioid Cells;
Female;
Fibrosis;
Giant Cells;
Humans;
Inflammation;
Lymphocytes;
Melkersson-Rosenthal Syndrome;
Vulva;
Vulvitis*
- From:Korean Journal of Dermatology
2013;51(11):912-915
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Granulomatous vulvitis is a rare localized inflammatory disease characterized by a painless, swollen, indurated and distorted vulva. Histopathologically, it shows chronic non-necrotizing granulomatous inflammation with edema, fibrosis, and lymphangiectasia. Some cases are associated with granulomatous cheilitis or Crohn's disease. So far, only a few cases of idiopathic granulomatous vulvitis have been reported. A 43-year-old female presented with a 1-year-history of persistent swelling of the vulva. The lesion was enlarged, edematous, and indurated, and there were clustered vesicles and papules on the labia major. Histopathologic examination of the swollen labia major showed granulomatous inflammation composed of multinucleated giant cells and epithelioid cells, with numerous lymphocytes in the dermis. Another biopsy specimen obtained from the clustered vesicles showed lymphangiectasia with chronic inflammation. Based on these characteristic histopathologic features and clinical findings, the patient was diagnosed with idiopathic granulomatous vulvitis. Herein, we reported a rare case of idiopathic granulomatous vulvitis that developed in a healthy woman.
