Solitary Fibrous Tumor of the Urinary Bladder.
10.3349/ymj.2004.45.3.573
- Author:
Se Hoon KIM
1
;
Kyung Bin CHA
;
Young Deuk CHOI
;
Nam Hoon CHO
Author Information
1. Department of Pathology, Yonsei University College of Medicine, Seoul, Korea. cho1988@yumc.yonsei.ac.kr
- Publication Type:Case Report ; Review
- Keywords:
Solitary fibrous tumor;
urinary bladder
- MeSH:
Bladder Neoplasms/*pathology;
Human;
Male;
Middle Aged;
Neoplasms, Fibrous Tissue/*pathology;
Tomography, X-Ray Computed
- From:Yonsei Medical Journal
2004;45(3):573-576
- CountryRepublic of Korea
- Language:English
-
Abstract:
Solitary fibrous tumor (SFT) is a distinct spindle cell tumor arising mainly in the pleura, however, SFT of extra-pleural sites had been reported. To our knowledge, five cases of the urinary bladder SFT had been reported. We have recently experienced a case of SFT of the urinary bladder in a 56-year- old man who was admitted to the hospital with a 4-month history of voiding difficulty, frequency, and residual urine sensation. A computerized tomography scan revealed a 12cm sized intravesical mass. The mass was marginally excised under the impression of it being a benign spindle cell tumor by pre-operative needle biopsy. On gross examination, the mass was multinodular, creamy white, and the cut surface was fibrotic with a rubbery consistency. Microscopic examination revealed haphazardly arranged spindle cells with a lace-like deposition of inter- and pericellular collagen. Areas of increased cellularity show nuclear atypia and occasional mitoses (2-3/10HPF). The immunohistochemical staining revealed an intense CD34 and bcl-2 immunoreactivity. Although the exact biologic behavior of these tumors has not been clarified, most of the reported cases have undergone a benign clinical course.
