Two Cases of Carbamazepine Induced Bradyarrhythmia: Potentially Lethal Side Effect in Elderly Patients.
- Author:
Jong Hee SOHN
1
;
Hyeo Il MA
;
Dae Hoon KIM
;
Kyung Ho YU
;
Seung Cheol JEONG
;
Byung Chul LEE
Author Information
1. Department of Neurology, Hallym University College of Medicine, Korea. ssbrain@med.hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Carbamazepine;
Arrhythmia;
Heart conduction
- MeSH:
Aged*;
Arrhythmias, Cardiac;
Bradycardia*;
Carbamazepine*;
Dyspnea;
Electrocardiography;
Humans;
Thorax;
United Nations
- From:Journal of the Korean Neurological Association
2002;20(4):407-409
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although potential hematologic complications of carbamazepine (CBZ) have been well known, the cardiac effects of CBZ are not widely appreciated. We report two cases of severe bradyarrhythmia induced by the usual dosage of CBZ. Two elderly patients complained of chest discomfort and dyspnea after CBZ medication. Their EKGs showed sinus bradycardia with junctional escape rhythm. After the discontinuation of CBZ, cardiac conduction abnormality were resolved. Even though cardiac side effect of CBZ is rare, it is potentially lethal in elderly patients.
