Rate of Isolation and Trends of Antimicrobial Resistance of Multidrug Resistant Pseudomonas Aeruginosa from Otorrhea in Chronic Suppurative Otitis Media.
- Author:
Sun Kyu LEE
1
;
Dong Choon PARK
;
Myung Gu KIM
;
Sung Hyun BOO
;
Young Joon CHOI
;
Jae Yong BYUN
;
Moon Suh PARK
;
Seung Geun YEO
Author Information
1. Department of Otolaryngology, Kyung Hee University School of Medicine, Seoul, Korea. yeo2park@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Pseudomonas aeruginosa;
Multidrug resistant;
Chronic suppurative otitis media
- MeSH:
Aminoglycosides;
Anti-Bacterial Agents;
Delivery of Health Care;
Humans;
Infection Control;
Otitis Media, Suppurative;
Pseudomonas;
Pseudomonas aeruginosa;
Quinolones
- From:Clinical and Experimental Otorhinolaryngology
2012;5(1):17-22
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: To assess the rate of isolation of Pseudomonas aeruginosa (PA) and multidrug-resistant PA (MDR-PA) from patients with chronic suppurative otitis media (CSOM) otorrhea and the annual trend of antibiotic-resistance. METHODS: Otorrhea samples were collected aseptically from 1,598 CSOM patients. The rate of bacterial isolation and the results of antibiotic susceptibility testing were evaluated retrospectively. RESULTS: The PA isolation rate from CSOM otorrhea was 24.4%. Of the 398 isolated strains tested for their susceptibilities to 10 antibiotics, 395 strains showed definitive results. Of these, 183 (46.3%) were susceptible to whole antibiotics and 212 (53.7%) was resistant to more than 1 antibiotics, with the frequency of antibiotics-resistance increasing significantly over time. Although strains susceptible to all antibiotics decreased over time, the rate of isolation of MDR-PA did not change significantly. Resistance to aminoglycosides and quinolones was higher than to other antibiotics and significantly increased over time, whereas resistance to other antibiotics showed no trend. CONCLUSION: MDR-PA, assessed using five individual antibiotics and six antibiotic-classes, showed no tendency to increase or decrease over time. This may have been due to increased concern about antibiotic-resistant bacterial strains, leading to improved infection control within hospitals and healthcare centers.
