A Clinical Study on 37 Cases of Oligodendroglioma.
- Author:
Ha Young KIM
1
;
Hee Won JUNG
;
Byung Kyu CHO
;
Dae Hee HAN
;
Je G CHI
;
Kil Soo CHOI
;
Bo Sung SIM
Author Information
1. Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cerebral glioma;
Oligodendroglioma;
Brain CR Recurrence rate;
Radiation therapy;
Pathologic grade
- MeSH:
Brain;
Brain Neoplasms;
Coloring Agents;
Diagnosis;
Female;
Frontal Lobe;
Glioma;
Humans;
Incidence;
Intracranial Hemorrhages;
Male;
Oligodendroglioma*;
Prognosis;
Recurrence;
Seizures;
Seoul;
Skull;
X-Ray Film
- From:Journal of Korean Neurosurgical Society
1986;15(4):671-680
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors reviewed 37 consecutive cases of histologically proven oligodendroglioma who were treated at the Seoul National University Hospital, between 1979 and 1986. There was a 1.5 : 1 male to female ratio. The age of patients at the time of diagnosis varied between 6 and 64 years(mean 38 years), with 51% in the fourth and fifth decades. The incidence of oligodendrogliomas represented 5% of all brain tumors and 15.5% of all gliomas. All but one were located supratentorially and 54% of them involved the frontal lobe. The mean duration of symptoms prior to the surgery was 27.2 months, but seizures had a considerably longer duration of 6.4 years. The common symptoms were headache(62%), seizures(38%), and motor weakness(22%). The common neurological findings were papilledema(51%), motor dificit(24%), and change in cognition(19%). Six out of 37 cases(16%) presented as the spontaneous intracranial hemorrhage. Calcifications were detected on plain X-ray films of the skull in 19% of patients and fine vascular stains were found on carotid angiograms in 30% of the cases. Brain CT revealed calcification(57%), cyst formation(43%), low density(35%) and heterogenous contrast enhancement(35%). The important factors affecting the prognosis and the recurrence rate were (1) the extent of surgical excision, (2) postoperative radiation therapy, and (3) the pathologic grading. There was a significant difference in the recurrence rate between patients treated with postoperative irradiation and patients treated with surgery alone.
