Effect of Pinealectomy on the Renin-Angiotensin System in Sprague-Dawley Rats.
- Author:
Yeon Chang MOON
1
;
Won Sun BAEK
;
Jong Moon KIM
Author Information
1. Department of Neurosurgery, College of Medicine, Won Kwang University, Chollabuk-do, Korea.
- Publication Type:Original Article
- Keywords:
Renin in pineal gland;
Angiotensin;
Renin-angiotensin system;
Cardiovascular system;
Pinealectomy
- MeSH:
Angiotensins;
Animals;
Blood Pressure;
Cardiovascular System;
Drinking;
Electrolytes;
Heart Rate;
Pineal Gland;
Pituitary Gland;
Plasma;
Rats;
Rats, Sprague-Dawley*;
Renin;
Renin-Angiotensin System*
- From:Journal of Korean Neurosurgical Society
1986;15(4):779-786
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Experiments were performed to investigate the effects of pinealectomy on the renin-angiotensin system in Sprague-Dawley rats. The results obtained were as follows. 1) There was no differences of systolic blood pressure, heart rate, water intake, and plasma electrolytes between pinealectomized and sham-operated rats. 2) Renin activity in plasma and pituitary gland did not differ in two experimental groups. 3) The pituitary gland contained the renin activity of about 50pg AI/hr/mg of wet weight. The results suggest that the pineal gland has no correlation with cardiovascular and renin-angiotensin system.
