Therapeutic Effects of Various Antibiotics for the Confluent and Reticulated Papillomatosis.
- Author:
Young Jo KIM
1
;
Bong Seok SHIN
;
Sung Han KIM
;
Kyu Chul CHOI
Author Information
1. Department of Dermatology, Chosun University, Gwangju, Korea. yjkim@chosun.ac.kr
- Publication Type:Original Article
- Keywords:
Confluent and reticulated papillomatosis;
Antibiotics;
Therapy
- MeSH:
Anti-Bacterial Agents*;
Doxycycline;
Erythromycin;
Follow-Up Studies;
Humans;
Minocycline;
Papilloma*;
Recurrence;
Tetracycline
- From:Korean Journal of Dermatology
2002;40(5):513-517
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Confluent and reticulated papillomatosis(CRP), the least common of the cutaneous papillomatoses, is manifested by persistent papules that are confluent in center and reticulated at the periphery. Recently, many cases of CRP treated with minocycline have been reported. METHODS: Thirteen patients with CRP were included in this study. They were treated with various antibiotics, such as erythromycin, tetracycline, doxycycline, and minocycline. The patients have taken antibiotics twice a day for 4 weeks. They were followed-up at 4, 8, 12, and 16 weeks after treatment. We assessed about therapeutic effects, side effects, and recurrence, by phone 1 year after treatment. RESULTS: Of the total 13 patients, 9 patients had improved by more than 95% in response to various antibiotics therapy for 4 months. One patient had a mild adverse reaction and two patients symptoms recurred after 1 year follow-up. CONCLUSION: We recommended various antibiotics therapy as the first choice of treatment for CRP because those were safe, economic, and effective.