A Case of Guttate Psoriasis in the Recipients of Allogeneic Bone Marrow Transplantation.
- Author:
Sook Kyoung KANG
1
;
Kyung Hyun ROH
;
Kyung Jeh SUNG
;
Kee Chan MOON
;
Jai Kyoung KOH
;
Jee Ho CHOI
Author Information
1. Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. jhchoy@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Guttate psoriasis;
Bone marrow transplantation
- MeSH:
Adolescent;
Autoimmune Diseases;
Bone Marrow Transplantation*;
Bone Marrow*;
Female;
Humans;
Immune System;
Keratinocytes;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Psoriasis*;
T-Lymphocytes
- From:Korean Journal of Dermatology
2002;40(5):532-535
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In many studies, it has been demonstrated that donor-derived cells would eventually replace the hematopoietic and immune system of the recipient after allogeneic bone marrow transplantation (BMT). And there are several case reports describing resolution or development of autoimmune diseases after BMT. Psoriasis is considered to be an autoimmune disease of abnormal keratinocyte proliferation induced by T lymphocytes. Herein we describe a 17-year-old woman presenting with guttate psoriasis, who suffered from acute lymphocytic leukemia and underwent allogeneic BMT 6 months ago. This is the first case of guttate psoriasis possibly associated with BMT in the Korean literature.