Primary Systemic Ki-1(CD30)-positive Large Cell Lymphoma.
- Author:
Min Jung WOO
1
;
Sung Woo LEE
;
Hyun CHUNG
;
Sang Won KIM
;
Ghil Suk YOON
Author Information
1. Department of Dermatology, Catholic University of Daegu School of Medicine, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
Ki-1(CD30) positive large cell lymphoma;
8-year old boy
- MeSH:
Child;
Cytoplasm;
Dermis;
Drug Therapy;
Giant Cells;
Humans;
Lymph Nodes;
Lymphoma*;
Male;
Skin;
Ulcer
- From:Korean Journal of Dermatology
2002;40(5):540-544
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of Ki-1(CD30) positive large cell lymphoma which developed on the skin of the right inguinal area in an 8-year-old boy. The lesion was a 3.0x5.0cm sized ulcerative tumor with elevated margin, rapidly growing during 2 week period and was associated with enlargement of the left inguinal lymph nodes. Histopathologic feature showed anaplastic large cells with abundant cytoplasm and multinucleated giant cells with wreath-like nuclei in the dermis and subcutis. Immunohistochemically, tumor cells were CD30 positive. He was treated with chemotherapy through BFM-NHL protocol, with good response.
