A Case of Darier' s Disease Improved with Oral Etretinate.
- Author:
Tai Young HAR
;
Sang Soo LEE
;
Moo Hyung LEE
;
Choong Rim HAW
- Publication Type:Case Report
- MeSH:
Acitretin*;
Edible Grain;
Darier Disease;
Etretinate*;
Female;
Forehead;
Humans;
Middle Aged;
Neck;
Skin
- From:Korean Journal of Dermatology
1988;26(2):250-254
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of Darier's disease occuring in 49-year-old female patient. She had hyperkeratotic crusted eruptions on her forehead, neck and posterior auricular area. The skin lesions aggravated in summer and improved in winter, but never been healed completely. Histopathologic features from neck lesions revealed hyperkeratosis with corps ronds and grains as well as formation of villi and laeunae. We treated her with oral etretinate, and she was almost completely free of disease after 3 months treatment. We suggested that etretinate is an importnat advance in the treatment of Darier's disease.