Prognostic Factors of Acute Renal Failure Patients Treated with Continuous Renal Replacement Therapy.
- Author:
Eui Sik KIM
1
;
Young Rok HAM
;
Won Ik JANG
;
Ji Yoon JUNG
;
O Kyoung KWON
;
Sarah CHUNG
;
Dae Eun CHOI
;
Ki Ryang NA
;
Kang Wook LEE
;
Young Tai SHIN
Author Information
1. Department of Internal Medicine, College of Medicine Chungnam National University, Daejeon, Korea. ytshin@cnu.ac.kr
- Publication Type:Original Article
- Keywords:
Renal Replacement Therapy;
Acute Renal Failure;
APACHE II;
Prognosis
- MeSH:
Acute Kidney Injury;
APACHE;
Critical Illness;
Fibrinogen;
Hemodiafiltration;
Hemofiltration;
Humans;
Multivariate Analysis;
Prognosis;
Prothrombin Time;
Renal Replacement Therapy;
Survivors
- From:Korean Journal of Nephrology
2010;29(1):54-63
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Continuous renal replacement therapy (CRRT) has been used widely for treating critically ill patients with acute renal failure (ARF). We performed this study to identify predictors of mortality in critically ill ARF patients treated with CRRT. METHODS: We analyzed the data of 128 patients who were treated with continuous veno-venous hemofiltration (CVVH) or continuous veno-venous hemodiafiltration (CVVHDF) from May, 2002 to March, 2008. We compared the clinical data of survivors with non-survivors. RESULTS: On univariate analyses of prognostic factors of patients treated with CVVHDF, APACHE II scores (p=0.004), prothrombin time (INR) (p=0.033) and the number of inotropics used (p=0.005) were significantly lower in survivors than those of non-survivors. MAP (p=0.027), diastolic BP (p=0.015) and fibrinogen level (p=0.007) were significantly higher in survivors than those of non-survivors. Multivariate analysis revealed that APACHE II scores and fibrinogen level were the independent factors for the prediction of mortality. And on univariate analyses of prognostic factors of patients treated with CVVH, APACHE II scores (p=0.002) and the number of inotropics used (p=0.006) were significantly lower in survivors than in non-survivors. MAP (p=0.03), systolic BP (p=0.02) and diastolic BP (p=0.03) were significantly higher in survivors than in non-survivors. Multivariate analysis also revealed that APACHE II scores was the only independent factor for the prediction of mortality. CONCLUSION: This study showed that the independent prognostic factor for mortality in ARF patients treated with CRRT was the APACHE II score.
