The Role of Positron-Emission Tomography in Diagnosis and Assessment of Treatment Response in Takayasu Arteritis.
- Author:
Se Woo PARK
1
;
Chang Hwa LEE
;
Gheun Ho KIM
;
Myung Ho JEONG
;
Soo Yuck PARK
;
Soon Yeong SONG
;
Yun Young CHOI
;
Chong Myung KANG
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Korea. kangjm@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Takayasu arteritis;
Positron-Emission Tomography;
Disease progression;
Diagnosis
- MeSH:
Aneurysm;
Angiography;
Arteries;
Biopsy;
Constriction, Pathologic;
Disease Progression;
Hand;
Humans;
Magnetic Resonance Angiography;
Positron-Emission Tomography;
Takayasu Arteritis
- From:Korean Journal of Nephrology
2010;29(1):115-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Takayasu arteritis is a nonspecific granulomatous inflammatory arteriopathy of unknown cause that results in occlusive obliteration and less commonly aneurysmal degeneration of large and medium-sized elastic arteries. The diagnosis of Takayasu arteritis and the assessment of its progression and extent remain challenging, especially in patients presenting with a constellation of non-specific symptoms and laboratory tests. The standard diagnostic procedures include biopsy, arteriography, sonography, and magnetic resonance angiography. However, these procedures are invasive or largely operator-dependent, and document only morphological changes such as stenosis, occlusion and aneurysmal transformation which mainly occur in late stages of the disease. On the other hand, Positron-emission tomography is an operator-independent, non-invasive metabolic imaging modality which plays a major role in diagnosis of nonspecific inflammatory diseases. We report a case in which Positron-emission tomography was applied to the detection of Takayasu arteritis and assessment of its disease progression.
