Studies on Plasma Renin and Aldosterone in Essential Hypertension.
10.4070/kcj.1974.4.2.1
- Author:
Jung Sang SONG
;
Sung Ho LEE
- Publication Type:Original Article
- MeSH:
Aldosterone*;
Blood Pressure;
Cholesterol;
Electrocardiography;
Furosemide;
Humans;
Hypertension*;
Hypertrophy, Left Ventricular;
Motor Activity;
Plasma*;
Potassium;
Proteinuria;
Renin*;
Sodium;
Triglycerides
- From:Korean Circulation Journal
1974;4(2):1-24
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Plasma renin activity (PRA) and aldosterone were measured to evaluate various status of clinical conditions in normal controls and patients with essential hypertension. Fourteen controls and 45 essential hypertensive patients for PRA, and 10 controls and 28 patients with essential hypertension for plasma aldosterone were studied. The results obtained are summarizing as follows. 1. Mean value of PRA of normal subjects was 2.9+/-1.4ng/ml/hr at rest, and 5.9+/-2.3ng/ml/hr by double stimulation, respectively, the latter elevated up to twice the former. 2. Mean value of PRA in the patients with essential hypertension was 3.37+/-3.0ng/ml/hr at rest, and 5.99+/-4.9ng/ml/hr by double stimulation. The latter have increased to 1.8 times the former. 3. The patients with low PRA observed in 33.3%, the normal in 42.2%, and the high in 22.5%, at rest. After double stimulation, the low group was observed in 22.2%, the normal in 60.0%, and the high in 17.8%. 4. Mean age of the patietns with low PRA was 57.2+/-2.6 years. Though it was higher than those of normal and high PRA groups(52.0+/-10.1 years), statistical significances were observed (0.05
