The comparison of oncologic and clinical outcomes of laparoscopic liver resection for hepatocellular carcinoma.
10.4174/astr.2014.86.2.61
- Author:
Sung Jin KIM
1
;
Hwa Kyung JUNG
;
Dong Shik LEE
;
Sung Su YUN
;
Hong Jin KIM
Author Information
1. Department of Surgery, Yeungnam University Medical Center, Daegu, Korea. hjkim@med.yu.ac.kr
- Publication Type:Original Article
- Keywords:
Laparoscopy;
Hepatectomy;
Hepatocellular carcinoma
- MeSH:
Carcinoma, Hepatocellular*;
Disease-Free Survival;
Hemorrhage;
Hepatectomy;
Humans;
Laparoscopy;
Liver*;
Operative Time;
Retrospective Studies;
Rupture;
Survival Rate;
Ultrasonography
- From:Annals of Surgical Treatment and Research
2014;86(2):61-67
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluate the operative outcome and oncologic outcome of laparoscopic liver resection for hepatocellular carcinoma (HCC), and compare with open liver resection. METHODS: From January 2004 to December 2012, clinical data of 70 patients who underwent laparoscopic liver resection for HCC (laparoscopic liver resection group, lapa-group) were collected and analyzed retrospectively. Control group (open liver resection group, open-group) were retrospectively matched, and compared with lapa-group. RESULTS: Laparoscopic major liver resections were performed in 4 patients. Laparoscopic anatomical resections and nonanatomical resections were performed in 39 patients, and 31 patients, respectively. Mean operative time was shorter in lapa-group (215.5 +/- 121.84 minutes vs. 282.30 +/- 80.34 minutes, P = 0.001), mean intraoperative transfusion rate and total amount were small in lapa-group (24.28%, 148.57 +/- 3,354.98 mL vs. 40.78%, 311.71 +/- 477.01 mL). Open conversion occurred in 6 patients (8.57%) because of bleeding, inadequate resection, invisible mass on intraoperative ultrasonography, and tumor rupture. In lapa-group and open-group, 3-year disease-free survival rates were 58.3% +/- 0.08%, and 62.6% +/- 0.06%, respectively (P = 0.773). In lapa-group and open-group 3-year overall survival rates were 65.3% +/- 0.8%, and 65.7% +/- 0.6%, respectively (P = 0.610). CONCLUSION: Laparoscopic liver resection for HCC is feasible and safe in a large number of patients, with reasonable operative and oncologic results.
