Analysis of Affecting Factors for Cortisol Level in Cord Blood.
- Author:
Hyun Jung LIM
1
;
Chang Hun SONG
;
Eun Young KIM
;
Sang Kee PARK
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Chosun University, Gwangju, Korea.
- Publication Type:Original Article
- Keywords:
Cord cortisol;
Stress during labor
- MeSH:
Apgar Score;
Fetal Blood*;
Fetus;
Humans;
Hydrocortisone*;
Infant, Newborn;
Parturition;
Prognosis;
Uterine Contraction
- From:Journal of the Korean Pediatric Society
2003;46(2):183-187
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Long-term stress to the fetus causes alterations in adrenal steroidogenesis. The purpose of this study was to analyze the association of cord blood cortisol with stress during delivery. METHODS: Cord blood samples were collected from 58 neonates at once to labor. Cortisol was measured by RIA method(DPC, USA). Cortisol level according to gestational age(<34, 34-37, >38 wks) and method of delivery(Cesarean section vs. vaginal delivery), Apgar score and uterine contraction, were compared to know stress during labor. RESULTS: Cortisol of cord blood had considerable differences between each group, according to gestational age(P<0.001). It was statistically higher in the cases of vaginal delivery than cessarian delivery(P<0.001). The concentration of cortisol was significantly higher according to duration of labor (P<0.05). There was a significant relationship between cortisol level and uterine contraction(P<0.05). The concentration of cortisol was significantly low when Apgar score at 1 min was low(P<0.05). CONCLUSION: Cord cortisol has close association with stress during labor. And so do with post birth prognosis of neonate.
