Four Cases of Scrub Typhus Treated with Azithromycin in Children.
- Author:
Eun Jung KIM
1
;
Chang Yoo LEE
;
Yeon Gyun OH
;
Hyang Suk YUN
;
Jong Duck KIM
Author Information
1. Department of Pediatrics, Wonkwang University, School of Medicine, Iksan, Korea. Chan33@be.md
- Publication Type:Case Report
- Keywords:
Tsutsugamushi fever;
Azithromycin;
Children
- MeSH:
Azithromycin*;
Child*;
Chloramphenicol;
Ciprofloxacin;
Ecosystem;
Female;
Fetus;
Humans;
Malaria;
Pregnant Women;
Scrub Typhus*;
Tetracycline;
Trombiculidae
- From:Journal of the Korean Pediatric Society
2003;46(2):188-191
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tsutsugamushi fever is a serious febrile disease outwardly similar to malaria and various arboviral infections. The endemic area is Asia-Pacific. This disease are generally associated with disturbed habitats favoring large populations of vector larval trombiculid mites. Therapy with tetracycline, chloramphenicol or ciprofloxacin is currently recommanded. Unfortunately these drugs is suboptimal for children and pregnant women. Recently, azithromycin has been proven to be effective in therapy of scrub typhus. There is no evidence that azithromycin causes adverse reaction to developing fetus or children. We report four cases of tsutsugamushi fever in children successfully treated with azithromycin. This is the first report describing clinical application of azithromycin to tsutsugamushi fever in Korean children.
