Comparison of Electroencephalography (EEG) Coherence between Major Depressive Disorder (MDD) without Comorbidity and MDD Comorbid with Internet Gaming Disorder.
10.3346/jkms.2017.32.7.1160
- Author:
Joohyung YOUH
1
;
Ji Sun HONG
;
Doug Hyun HAN
;
Un Sun CHUNG
;
Kyoung Joon MIN
;
Young Sik LEE
;
Sun Mi KIM
Author Information
1. Department of Psychiatry, Chung-Ang University Medical Center, Seoul, Korea. sunmikim706@gmail.com
- Publication Type:Original Article
- Keywords:
Internet Gaming Disorder;
Major Depressive Disorder;
Quantitative Electroencephalogram;
Coherence
- MeSH:
Comorbidity*;
Depressive Disorder, Major*;
Electrodes;
Electroencephalography*;
Humans;
Immunoglobulin D;
Internet*;
Male
- From:Journal of Korean Medical Science
2017;32(7):1160-1165
- CountryRepublic of Korea
- Language:English
-
Abstract:
Internet gaming disorder (IGD) has many comorbid psychiatric problems including major depressive disorder (MDD). In the present study, we compared the neurobiological differences between MDD without comorbidity (MDD-only) and MDD comorbid with IGD (MDD+IGD) by analyzing the quantitative electroencephalogram (QEEG) findings. We recruited 14 male MDD+IGD (mean age, 20.0 ± 5.9 years) and 15 male MDD-only (mean age, 20.3 ± 5.5 years) patients. The electroencephalography (EEG) coherences were measured using a 21-channel digital EEG system and computed to assess synchrony in the frequency ranges of alpha (7.5–12.5 Hz) and beta (12.5–35.0 Hz) between the following 12 electrode site pairs: inter-hemispheric (Fp1–Fp2, F7–F8, T3–T4, and P3–P4) and intra-hemispheric (F7–T3, F8–T4, C3–P3, C4–P4, T5–O1, T6–O2, P3–O1, and P4–O2) pairs. Differences in inter- and intra-hemispheric coherence values for the frequency bands between groups were analyzed using the independent t-test. Inter-hemispheric coherence value for the alpha band between Fp1–Fp2 electrodes was significantly lower in MDD+IGD than MDD-only patients. Intra-hemispheric coherence value for the alpha band between P3–O1 electrodes was higher in MDD+IGD than MDD-only patients. Intra-hemispheric coherence values for the beta band between F8–T4, T6–O2, and P4–O2 electrodes were higher in MDD+IGD than MDD-only patients. There appears to be an association between decreased inter-hemispheric connectivity in the frontal region and vulnerability to attention problems in the MDD+IGD group. Increased intra-hemisphere connectivity in the fronto-temporo-parieto-occipital areas may result from excessive online gaming.
