The Value of Bone Scan for Detection of Bone Metastasis of Prostatic Cancer.
- Author:
Hyun Moo LEE
1
;
June Key CHUNG
;
Sang Eun LEE
;
Young Kyoon KIM
Author Information
1. Department of Urology and Internal*, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
prostate cancer;
bone scan;
metastasis
- MeSH:
Acid Phosphatase;
Alkaline Phosphatase;
Humans;
Neoplasm Metastasis*;
Prostatic Neoplasms*;
Radiography;
Technetium
- From:Korean Journal of Urology
1987;28(1):13-17
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The nuclear bone scan is a highly sensitive means of detecting skeletal metastases in patients with prostatic cancer. The results of bone scan with technetium 99m-labeled methylene diphosphonate in 61 patients with biopsy-proven primary prostatic cancer demonstrated bone metastases in 60.7% of cases. The addition of bone scanning to radiographic survey increased the detection rate of bone metastasis by 45.2% and only 1 patient had abnormal roentgenograms but normal scans, a yield of 5.3% false-negative scans. Of those with proved bone metastases by bone scan with radiography, 44.4% had no bone pain, 55.6% had normal acid phosphatase level and 3l.2% had normal alkaline phosphatase levels. Of those without bone metastases by bone scan with radiography, 4.3% had bone pain, 9.1% had elevated acid phosphatase levels and 9.1% had elevated alkaline phosphatase levels.
