Two Cases of Pseudomelanosis Duodeni Associated with Systemic Diseases and Oral Iron Supplementation.
- Author:
Kyoung Hwan LEE
1
;
Tae Hoon LEE
;
Yun Suk SHIM
;
Jun Ho CHOI
;
Il Kwun CHUNG
;
Sang Heum PARK
;
Sun Joo KIM
;
Mee Hye OH
Author Information
1. Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Korea. thlee9@lycos.co.kr
- Publication Type:Case Report
- Keywords:
Melanosis;
Hemosiderin;
Duodenum
- MeSH:
Diabetes Mellitus;
Duodenum;
Hemosiderin;
Humans;
Hypertension;
Iron;
Melanosis;
Mucous Membrane;
Natural History;
Pigmentation;
Renal Insufficiency, Chronic
- From:Korean Journal of Gastrointestinal Endoscopy
2009;39(6):374-378
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pseudomelanosis duodeni is a rare benign condition that manifests endoscopically as diffuse, small brownish-black spots in the duodenal mucosa, and the histochemical findings show an accumulation of hemosiderin pigment in the duodenal villi's lamina propria. This condition produces no specific symptoms, and it may be reversible. The cause and natural history of the pigmentation have not been clarified, although it is associated with a variety of systemic illnesses and medications. We describe two cases of pseudomelanosis duodeni and the patients had histories of diabetes mellitus, hypertension, chronic renal insufficiency and specific medications. We also review the relevant medical literature on this rare condition.
