Usefulness and Limitation of 2010 ACR/EULAR Classification Criteria in Korean Patients with Early RA.
10.4078/jrd.2012.19.6.326
- Author:
Su Jin MOON
1
;
Chang Hoon LEE
;
Yun Sung KIM
;
Yun Jung PARK
;
Kwi Young KANG
;
Seung Ki KWOK
;
Hae Rim KIM
;
Ji Hyeon JU
;
Hyun Sook KIM
;
Young Il SEO
;
Sang Tae CHOI
;
Jin Jung CHOI
;
Hyun Ah KIM
;
Wan Uk KIM
;
Chong Hyun YOON
;
Yeon Sik HONG
;
Myeung Su LEE
;
Sang Heon LEE
;
Jung Soo SONG
;
Won PARK
;
Ho Youn KIM
;
Sung Hwan PARK
Author Information
1. Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, Korea. rapark@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Rheumatoid arthritis;
Criterion;
Diagnosis;
Seronegative
- MeSH:
Arthritis, Rheumatoid;
Female;
Hand;
Humans;
Republic of Korea;
Rheumatic Diseases;
Tertiary Care Centers
- From:Journal of Rheumatic Diseases
2012;19(6):326-333
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The 2010 New American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria for rheumatoid arthritis (RA) was raised to identify patients with early RA and replaced the 1987 ACR classification criteria. The aims of this study are to assess the availability of new classification criteria and to evaluate its potential limitation. METHODS: A total of 408 patients with newly diagnosed RA were included from 13 secondary or tertiary hospitals in South Korea. The symptom duration was less than 12 months before the diagnosis of RA. RA was defined as either 1987 ACR classification criteria or new 2010 ACR/EULAR criteria. We compared the full details of both classification criteria. RESULTS: The mean symptom duration was 5.1 months. The majority (76.2%) of the patients were female. Two hundred and seventy three patients (66.9%) fulfilled both of the 2010 and 1987 classification criteria. Forty-seven (14.7%) of the 320 patients fulfilling the 1987 criteria did not fulfill the new classification criteria. On the other hand, eighty-eight (24.4%) of the 361 patients fulfilling the 2010 ACR/EULAR classification criteria did not fulfill the 1987 ACR criteria. Thirty-six (55.4%) of the 65 patient with seronegative RA failed to meet the 2010 classification criteria. In case of seropositive RA (n=343), 85 additional patients (24.8%) could be diagnosed as RA using new classification criteria. CONCLUSION: The new 2010 ACR/EULAR classification criteria enable physicians to diagnose more patients with early RA via the help of serology. However, the sensitivity for the diagnosis of seronegative RA is projected to decrease.
