A Case of Pediatric-onset Mixed Connective Tissue Disease Presenting Raynaud's Phenomenon Affecting Tongue, Hands, and Feet.
10.4078/jrd.2012.19.6.344
- Author:
Soon Myung JUNG
1
;
Jin Taek YOO
;
Young Hwan KIM
;
Yu Na SEO
;
Na Young LEE
;
Seong Geun LEE
;
Seong Hu PARK
;
Young Eun PARK
;
Seung Hoon BAEK
;
Geun Tae KIM
;
Sung Il KIM
;
Joung Wook LEE
Author Information
1. Department of Internal Medicine, Busan St. Mary's Medical Center, Busan, Korea. gesundheit@paran.com
- Publication Type:Case Report
- Keywords:
Pediatric-onset mixed connective tissue disease;
Raynaud's phenomenon;
Antibody to ribonucleoprotein
- MeSH:
Child;
Female;
Foot;
Hand;
Humans;
Lupus Erythematosus, Systemic;
Mixed Connective Tissue Disease;
Rheumatology;
Scleroderma, Systemic;
Tongue;
United States
- From:Journal of Rheumatic Diseases
2012;19(6):344-347
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mixed connective tissue disease (MCTD) was first described by Sharp and coworkers in 1972, characterized by symptoms of Raynaud's phenomenon or swollen hands, overlapping clinical features of systemic lupus erythematosus, systemic sclerosis, or polymyositis/dermatomyositis, and the presence of anti-U1 RNP antibody. MCTD is rare in children and constitutes 0.3~0.6% of all rheumatologic patients in pediatric rheumatology database of the United States. Here, we report the first Korean case of a 10-year-old female patient with MCTD, presenting Raynaud's phenomenon in the hands, feet, and tongue.
