A Case of Sarcoidosis Combined with Massive Ascites.
10.4078/jrd.2012.19.6.364
- Author:
Su Jin LEE
1
;
Eun Hye KIM
;
Young Sook KIM
;
Je Eun SONG
;
Soo Jin CHUNG
;
Chun Kyun LEE
;
Myung Hee CHANG
;
Jung Gu KANG
;
Yoon Jung CHOI
;
Su Mi PARK
;
Chan Hee LEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Sarcoidosis;
Massive ascites;
Liver involvement;
Peritoneal involvement;
Methotrexate
- MeSH:
Abdomen;
Adrenal Cortex Hormones;
Ascites;
Biopsy;
Eye;
Fibrosis;
Granuloma;
Humans;
Inflammation;
Liver;
Lung;
Lymph Nodes;
Lymphatic Diseases;
Male;
Methotrexate;
Sarcoidosis;
Skin;
Weight Loss
- From:Journal of Rheumatic Diseases
2012;19(6):364-368
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sarcoidosis is a multi-systemic granulomatous disease of unknown cause, which most commonly involves lung, skin, eye, liver and lymph nodes. Herein, we report a case of sarcoidosis presented with massive ascites. A 47-year-old male patient visited our hospital with symptoms of general weakness and weight loss from past 4 months. Abdomen computed tomography showed multiple lymphadenopathy and hepatosplenomegaly. Lymph node biopsy demonstrated non-caseating granulomas. After biopsy, development of massive uncontrolled ascites was noted. Liver biopsy showed non-cirrhotic hepatic and portal fibrosis and omental biopsy showed submesothelial diffuse fibrosis and focal chronic inflammation, which were suggestive of hepatic and peritoneal involvement in sarcoidosis. Ascites was controlled after subsequent treatment with corticosteroids and methotrexate.
